Dorsomorphin dihydrochloride
产品编号: DC7115
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应用领域
Dorsomorphin dihydrochloride (BML-275 dihydrochloride; Compound C dihydrochloride) 是一种有效，选择性和 ATP 竞争性的 AMPK 抑制剂，Ki 为 109 nM。Dorsomorphin dihydrochloride 通过靶向抑制 I 型受体 ALK2，ALK3 和 ALK6 来抑制 BMP 途径。Dorsomorphin dihydrochloride 诱导自噬 (autophagy) 作用。
| Cas No.: |
1219168-18-9 |
| 名称: |
6-[4-(2-piperidin-1-ylethoxy)phenyl]-3-pyridin-4-ylpyrazolo[1,5-a]pyrimidine |
| 别名: |
BML-275; Compound C; BML275; BML 275 |
| SMILES: |
C1CCN(CC1)CCOC2=CC=C(C=C2)C3=CN4C(=C(C=N4)C5=CC=NC=C5)N=C3.Cl.Cl |
| 分子式: |
C24H27Cl2N5O |
| 分子量: |
472.41 |
| 纯度: |
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| 保存条件: |
2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
| Description: |
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| References: |
Dorsomorphin is a selective inhibitor of Bone morphogenetic protein (BMP) signaling. It has been found to inhibit BMP signals required For embryogenesis and promoted significant neural differentiation from human pluripotent stem cell (hPSC) lines. Dorsom |
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MSDS
| TITLE |
DOWNLOAD |
| MSDS_1563_DC7115_1219168-18-9 |
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COA
| LOT NO. |
DOWNLOAD |
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