EX-229
产品编号: DC11634
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应用领域
EX229 是一个苯并咪唑的衍生物，是 AMP 活化蛋白激酶 (AMPK) 的有效变构激动剂，其对 α1β1γ1、α2β1γ1 和 α1β2γ1 的 Kd 值分别为 0.06 μM、0.06 μM 和 0.51 μM。
| Cas No.: |
1219739-36-2 |
| 名称: |
5-{[6-chloro-5-(1-methylindol-5-yl)-1H-benzimidazol-2-yl]oxy}-2-methyl-benzoic acid |
| 别名: |
EX 229;EX229 |
| SMILES: |
C(O)(=O)C1=CC(OC2NC3=CC(Cl)=C(C4C=CC5=C(C=4)C=CN5C)C=C3N=2)=CC=C1C |
| 分子式: |
C24H18ClN3O3 |
| 分子量: |
431.876 |
| 纯度: |
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| 保存条件: |
2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
| Description: |
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| References: |
A small molecule AMPK activator that dose-dependently increases AMPK activity of α1-, α2-, β1- and β2-containing complexes at 50 uM; induces AMPK activation and glucose uptak in a wortmannin-independent manner; increases fatty acid oxidation in L6 myotubes. |
| Kinase Assay: |
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MSDS
| TITLE |
DOWNLOAD |
| MSDS_829_DC11634_1219739-36-2 |
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COA
| LOT NO. |
DOWNLOAD |
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询盘
