ML216
产品编号: DC7771
Featured
我们的合作伙伴:
中国地区超过5000个高品质化合物库存
应用领域
ML216 (CID-49852229) 是一种有效，选择性，细胞渗透性的 BLM 解旋酶抑制剂，对 BLMfull-length 和 BLM636-1298 的 IC50 分别为 2.98 μM 和 0.97 μM。ML216 以 Ki 为 1.76 µM 来抑制 BLM 的 ssDNA 依赖性 ATPase 的活性。ML216 具有抗肿瘤活性。
| Cas No.: |
1430213-30-1 |
| 名称: |
|
| 别名: |
ML 216; ML-216; CID-49852229; CID49852229; CID 49852229 |
| SMILES: |
N(C1=CC=C(F)C(C(F)(F)F)=C1)C(NC1=NN=C(C2C=CN=CC=2)S1)=O |
| 分子式: |
C15H9F4N5Os |
| 分子量: |
383.32 |
| 纯度: |
|
| 保存条件: |
2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
| Description: |
|
| In Vivo: |
|
| In Vitro: |
|
| References: |
ML216(CID-49852229) is a potent inhibitor of the DNA unwinding activity of BLM helicase; showing similar IC50s of 3.0 and 0.97 μM for full length BLM and BLM636–1298 respectively.
IC50 value: 3.0/0.97 uM(Full length/636–1298 BLM)
Target: BLM helicase inhi |
| Kinase Assay: |
|
| Cell Assay: |
|
| Animal Administration: |
|
| References: |
|
MSDS
| TITLE |
DOWNLOAD |
| MSDS_1955_DC7771_1430213-30-1 |
|
COA
| LOT NO. |
DOWNLOAD |
|
|
询盘
