HUHS015
产品编号: DC9697
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应用领域
HUHS015 是一种高效的 PCA-1/ALKBH3 抑制剂，对 PCA-1 作用的 IC50 值为 0.67 μM。
| Cas No.: |
1453097-13-6 |
| 名称: |
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| 别名: |
HUHS-015,HUHS 015 |
| SMILES: |
CC1=CC2=C(C=C1)N=C(N2)N3C(=O)C(=C(N3)C)CC4=CC=CC=C4 |
| 分子式: |
C19H18N4O |
| 分子量: |
318.37 |
| 纯度: |
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| 保存条件: |
2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
| Description: |
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| In Vivo: |
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| In Vitro: |
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| References: |
HUHS015 is a potent PCA-1/ALKBH3 inhibitor both in vitro and in vivo. The bioavailability (BA) of HUHS015 was 7.2% in rats after oral administration. Continuously administering HUHS015 significantly suppressed the growth of DU145 cells, which are human hormone-independent prostate cancer cells, in a mouse xenograft model without untoward effects. |
| Kinase Assay: |
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| Cell Assay: |
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| Animal Administration: |
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| References: |
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MSDS
COA
| LOT NO. |
DOWNLOAD |
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| 2018-0101 |
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询盘
