SR-3029
产品编号: DC9782
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应用领域
SR-3029 是一种有效的，ATP 竞争性的 CK1δ 和 CK1ε 的抑制剂，IC50 值分别为 44 nM 和 260 nM，Ki 均为 97 nM。
| Cas No.: |
1454585-06-8 |
| 名称: |
(6,7-Difluoro-1H-benzoimidazol-2-ylmethyl)-[9-(3-fluoro-phenyl)-2-morpholin-4-yl-9H-purin-6-yl]-amine |
| 别名: |
SR3029,SR 3029 |
| SMILES: |
C1COCCN1C2=NC3=C(C(=N2)NCC4=NC5=C(N4)C=CC(=C5F)F)N=CN3C6=CC(=CC=C6)F |
| 分子式: |
C23H19F3N8O |
| 分子量: |
480.45 |
| 纯度: |
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| 保存条件: |
2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
| Description: |
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| References: |
SR 3029 is a potent and highly specific CK1δ/CK1ε inhibitor with the IC50 of 97 nM.
SR-3029 exhibits in vitro and in vivo PK properties suitable for use in xenograft studies of human cancers, including brain cancers.Meanwhile it can also Inhibits Breast Cancer Cell Growth and Survival and impairs orthotopic breast tumor growth in vivo. In animal injection, SR-3029 (20 mg/kg daily i.p.). |
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MSDS
| TITLE |
DOWNLOAD |
| MSDS_2794_DC9782_1454585-06-8 |
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COA
| LOT NO. |
DOWNLOAD |
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