IC-261(SU-5607)
产品编号: DC9730
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应用领域
IC261 是一种选择性的，ATP 竞争性的 CK1 抑制剂，对 Ckiδ，Ckiε 和 Ckiα1 的 IC50 值分别为 1 μM，1 μM 和 16 μM。
| Cas No.: |
186611-52-9 |
| 名称: |
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| 别名: |
IC261,SU5607,IC 261,SU 5607 |
| SMILES: |
COC1=CC(=C(C(=C1)OC)C=C2C3=CC=CC=C3NC2=O)OC |
| 分子式: |
C18H17NO4 |
| 分子量: |
311.33 |
| 纯度: |
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| 保存条件: |
2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
| Description: |
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| In Vitro: |
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| References: |
IC261 is a specific inhibitor of the protein kinases casein kinase 1-delta and -epsilon, triggers the mitotic checkpoint and induces p53-dependent postmitotic effects. At low micromolar concentrations IC261 inhibits cytokinesis causing a transient mitotic arrest. IC261 selectively inhibits CK1 compared to other protein kinases by an ATP-competitive mechanism. |
| Kinase Assay: |
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| Cell Assay: |
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| Animal Administration: |
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| References: |
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MSDS
| TITLE |
DOWNLOAD |
| MSDS_2749_DC9730_186611-52-9 |
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COA
| LOT NO. |
DOWNLOAD |
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询盘
