Roxadustat(FG-4592)
产品编号: DC5193
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应用领域
Roxadustat (FG-4592) 是一种口服 低氧诱导因子脯氨酰羟化酶 抑制剂 (HIF-PHI)，通过增加内源性促红细胞生成素、改善铁调节和降低铁调素来促进红细胞生成。
| Cas No.: |
808118-40-3 |
| 名称: |
2-(4-hydroxy-1-methyl-7-phenoxyisoquinoline-3-carboxamido)acetic acid |
| 别名: |
Roxadustat,ASP1517,ASP-1517,FG 4592，FG4592 |
| SMILES: |
CC1=NC(=C(C2=C1C=C(C=C2)OC3=CC=CC=C3)O)C(=O)NCC(=O)O |
| 分子式: |
C19H16N2O5 |
| 分子量: |
352.34 |
| 纯度: |
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| 保存条件: |
2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
| Description: |
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| In Vitro: |
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| References: |
FG-4592 is an inhibitor of hypoxia inducible factor (HIF) prolyl hydroxylase currently in clinical development For the treatment of anemia. FG-4592 stabilizes the activities of HIF, a cytosolic transcription factor, leading to activation of the genes ass |
| Kinase Assay: |
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| Cell Assay: |
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| Animal Administration: |
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| References: |
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MSDS
COA
| LOT NO. |
DOWNLOAD |
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| 2018-0101 |
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