| Cas No.: | 1391712-60-9 |
| 名称: | (S)-2-((5-chloro-2-((6-(4-(2-hydroxyethyl)piperazin-1-yl)-1-methoxy-6,7,8,9-tetrahydro-5H-benzo[7]annulen-2-yl)amino)pyrimidin-4-yl)amino)-N-methylbenzamide |
| 别名: | CEP37440,CEP 37440 |
| SMILES: | CNC(=O)C1=CC=CC=C1NC2=NC(=NC=C2Cl)NC3=C(C4=C(CC(CCC4)N5CCN(CC5)CCO)C=C3)OC |
| 分子式: | C30H38ClN7O3 |
| 分子量: | 580.12 |
| 纯度: | |
| 保存条件: | 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
| Description: | |
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| References: | CEP-37440 is a novel potent and selective Dual FAK/ALK inhibitor with IC50 s of 2.3 nM (FAK) and 120 nM(ALK cellular IC50 in 75% human plasma).Preparation of fused bicyclic 2,4-diaminopyrimidine derivatives as a dual ALK and FAK inhibitor By Jacobs, Martin J.; Ott, Gregory R. From PCT Int. Appl. (2013), WO 2013134353 A1 20130912. For the detailed information of CEP-37440, the solubility of CEP-37440 in water, the solubility of CEP-37440 in DMSO, the solubility of CEP-37440 in PBS buffer, the animal experiment (test) of CEP-37440, the cell expriment (test) of CEP-37440, the in vivo, in vitro and clinical trial test of CEP-37440, the EC50, IC50,and affinity,of CEP-37440, Please contact DC Chemicals. |
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MSDS
| TITLE | DOWNLOAD |
| MSDS_2069_DC8009_1391712-60-9 |
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COA
| LOT NO. | DOWNLOAD |
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